Toward Structure-based Drug-Discovery for SETBP1

Awardee: Jerome Baudry

Institution: The University of Alabama in Huntsville

Grant Amount: $45,733

Funding Period: February 1, 2022 - January 31, 2023

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Summary:

We will start the first drug discovery pipeline toward finding a pharmaceuticals that can counter the effect of SETBP1 mutations. We will use very powerful computers to predict how mutated SETBP1 interacts with its partners in the cell, and we will identify small molecules that can correct the problems.