Awarded Grants

 

The ODC offers over 50 grant opportunities in 30+ disease areas annually to researchers across the globe, as well as within the Penn and CHOP communities. Since 2011, the ODC has funded 400 awards totaling $40,269,515 to 120+ institutions in 25 countries worldwide

See below for a complete list of ODC-awarded grants since 2011.

 
 
 

Awarded Grants

Featured
Investigating clonal expansion of pathogenic T cells in idiopathic multicentric Castleman disease

David Fajgenbaum

University of Pennsylvania

$58,775

Targeting biomolecular condensates, as a novel approach to ameliorate SYNGAP1-related synaptopathy

Kristian Strømgaard

University of Copenhagen

$74,851

Mapping Molecular and Behavioral Impacts of SETBP1 Deficiency in Zebrafish

Alexander Little

McMaster University

$68,544

Assessing Excitation-Transcription Coupling in SCN2A-Related Disorder Mouse Models

Jennifer Kearney

Northwestern University

$62,492

Leveraging Human iPSC Derived Beta Cells to Investigate the Impact of Novel Therapeutics in Patients with Congenital Hyperinsulinism

Mansa Krishnamurthy

Cincinnati Children's Hospital Medical Center

$77,165

Safety, Accuracy, and Feasibility of Continuous Glucose Monitoring in Infants in the Inpatient NICU Setting with Hyperinsulinism and Hypoglycemia

Paul Thornton

Cook Children's Medical Center

$77,165

Tcf4 in gut development; investigating underlying causes of gastro-intestinal problems in patients with Pitt Hopkins syndrome

Simone Mesman

University of Amsterdam

$58,602

Transcriptomic Signatures in Neuroendocrine Cell Hyperplasia of Infancy (NEHI)

Sharon McGrath-Morrow

Children's Hospital of Philadelphia

$83,154

Bronchoalveolar Lavage Fluid-Derived Organoids as Translational Models for Neuroendocrine cell hyperplasia of infancy

James Hagood

University of North Carolina

$83,154

Quantifying Movement Patterns in Children with STXBP1 Related Disorders

Laura Prosser

Children's Hospital of Philadelphia

$69,708

A deep screen of RNA-based therapeutics for STXBP1 syndrome

Chaolin Zhang

The Trustees of Columbia University in the City of New York

$69,708

Exploring the profile of Extracellular Vesicles (EVs) in Lesch-Nyhan Syndrome (LNS)

Giulia Bernardini

Università degli Studi di Siena, Dipartimento di Biotecnologie, Chimica e Farmacia

$57,332

Deciphering the role of ephrin B2 mutation in the pathogenesis of central conducting lymphatic anomaly

Shoshana Greenberger

Newcastle University

$62,398

Serum biomarkers for diagnosis and sirolimus response in lymphangioleiomyomatosis

Elizabeth P Henske

Brigham and Women's Hospital, Harvard Medical School

$73,958

Deciphering the splicing order of COL6A1-3 pre-mRNAs to improve the prognosis and treatment of collagen VI-related muscular dystrophies

Karine Choquet

Université de Sherbrooke

$46,611

Novel insights into cellular interaction in collagen VI muscular dystrophy

Malte Tiburcy

University Medical Center Göttingen

$46,611

From mouse to human – Establishing novel biomarkers for APBD

Felix Nitschke

University of Texas Southwestern Medical Center

$56,857

Development of glycogen synthase inhibitors for APBD

Wyatt Yue

Newcastle University

$56,857

Small molecule inhibition of NOTCH3 conformational alterations

Michael Wang

University of Michigan

$101,776

Understanding the role of the lipid transport protein VPS13B in Cohen syndrome pathogenesis

Berrak Ugur

Yale University

$98,828

Using human retinal organoids to discover mechanisms and therapies for CRB1 retinopathy

Brian Ballios

University Health Network

$66,991

Deciphering perturbations of primary cilia in Okur-Chung neurodevelopmental disorder

Abdelhalim Loukil

Sanford Research Institute

$60,013

In Vivo, Non-Viral Base Editing To Correct AT Variants In Brain, Blood, Lung, and Liver

Xizhen Lian

Johns Hopkins University

$41,740

Investigating Excitation/Inhibition Balance in Cortical-Thalamic Circuitry in CDKL5 Deficiency Disorder Using Human-Derived Assembloids

Francesca Puppo

University of California, San Diego

$61,007

Epilepsy linked toTBC1D24 Loss: pH-Targeted Pharmacological and Nanotechnological Interventions

Caterina Michetti

University of Genoa

$62,937

An iPSC-based Platform for Characterization of Neuronal Circuit Dysfunction in RASopathies

Sattar Khoshkhoo

Brigham and Women's Hospital

$58,222

Investigating SETBP1 pathogenic variants in lung malformation and function using human induced pluripotent stem cell-derived organoids

Amy Wong

Toronto Hospital for Sick Children

$70,000

A novel RNA therapeutic for the treatment of CTNNB1 syndrome

Jeff Coller

Johns Hopkins University

$63,312

A comprehensive functional analysis of Dup15q ‎genes: phenotypic effects and treatment ‎following restoration‎

Alon Zaslaver

The Hebrew University

$47,038

Molecular and Functional Mechanisms Underlying Cortical Activity in CACNA1A Epilepsy

Fikri Birey

Emory University

$57,450

 
 

For complete grant list click here