Probing Central and Peripheral Mechanisms of Pain and Dysfunction in Fibrous Dysplasia/McCune-Albright

MDBRFDMAS
Written By Million Dollar Bike Ride

Awardee: Jaymin Upadhyay

Institution: Boston Children's Hospital

Grant Amount: $40,321.00

Funding Period: February 1, 2024 - January 31, 2025

Summary:

Pain remains a multifaceted and often poorly treated symptom in Fibrous Dysplasia/McCune-Albright (FD/MAS). In this project, we propose to identify and treat biopsychosocial or centralized aspects of pain in FD/MAS. We hope to expand upon what is currently understood about pain in FD/MAS and work towards providing improved treatment options to patients with FD/MAS.

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Spatial transcriptomics to elucidate the mechanism of anti-RANKL inhibition of fibrous dysplasia bone lesions
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