Visualizing the effect of CDKL5 deficiency on ciliary core structures

CDKL5CDKL5 Pilot Grant Programme

Jul 1

Written By Million Dollar Bike Ride

Awardee: Alan Brown, PhD

Institution: Harvard Medical School

Award Amount: $150,000

CDKL52020

Million Dollar Bike Ride

Elucidate the neural mechanisms underlying sleep disturbances and the relation between seizures and sleep-wake cycle in CDKL5 deficiency disorder (CDD)

Incorporation of functional unnatural amino acids into CDKL5 to study its function in cells