Awarded Grants
Awarded Grants
Assessment of the therapeutic potential of TATk-hCDKL5 isoform 1 and 2 produced in recombinant Antarctic Pseudoalteromonas haloplanktis TAC125
Maria Luisa Tutino, PhD
University Federico II of Naples
$149,985.00
Awardee: Maria Luisa Tutino, PhD
Institution: University Federico II of Naples
Award Amount: $149,985.00
Funding Period: May 1, 2023 - April 31, 2024
Therapeutic potential of Ca2.3 inhibitors in CDD mouse and human models
Marisol Sampedro Castanedo, PhD
Francis Crick Institute
$149,942.00
Awardee: Marisol Sampedro Castanedo, PhD
Institution: Francis Crick Institute
Award Amount: $149,942.00
Funding Period: May 1, 2023 - April 31, 2024
New Drosophila models of CDD
Maximo Ibo Galindo
Centro de Investigación Príncipe Felipe
$148,950.00
Awardee: Maximo Ibo Galindo, PhD
Institution: Centro de Investigación Príncipe Felipe
Award Amount: $148,950.00
Funding Period: May 1, 2023 - April 31, 2024
Utilizing patient iPSC-derived neurons to determine the functional consequences of longer cilia in CDKL5 Deficiency Disorder (CDD)
Mustafa Sahin, MD PhD
Boston Children’s Hospital
$149,241
Awardee: Mustafa Sahin, MD PhD
Institution: Boston Children’s Hospital
Award Amount: $149,241
Funding Period: May 1, 2022 - April 31, 2023
Computational drug repurposing for CDKL5 Deficiency Disorder
Diego Di Bernardo, PhD
Telethon Institute of Genetics and Medicine
$150,000
Awardee: Diego Di Bernardo, PhD
Institution: Telethon Institute of Genetics and Medicine
Award Amount: $150,000
Funding Period: May 1, 2022 - April 31, 2023
Rescuing functional defects in a zebrafish model of CDKL5 deficiency: Contribution to the identification of therapeutic target
M. Leonor Cancela, PhD
University of Algarve
$141,338
Awardee: M. Leonor Cancela, PhD
Institution: University of Algarve
Award Amount: $141,338
Funding Period: May 1, 2022 - April 31, 2023
A functional genomics approach to dissect the molecular bases of CDKL5 Deficiency Disorder
Davide Cacchiarelli, PhD
Telethon Institute of Genetics and Medicine
$150,000
Awardee: Davide Cacchiarelli, PhD
Institution: Telethon Institute of Genetics and Medicine
Award Amount: $150,000
Funding Period: May 1, 2022 - April 31, 2023
Hematopoietic stem cell gene therapy as a therapeutic approach for CDKL5 Deficiency Disorder
Joseph Anderson, PhD
University of California, Davis
$150,000
Awardee: Joseph Anderson, PhD
Institution: University of California, Davis
Award Amount: $150,000
Funding Period: May 1, 2022 - April 31, 2023
ASO therapy in CDKL5 deficiency disorder
Michela Fagiolini, PhD
Boston Children's Hospital
$150,000
Awardee: Michela Fagiolini, PhD
Institution: Boston Children's Hospital
Award Amount: $150,000
Funding Period: May 1, 2021 - April 31, 2022
Comparison of Brain Biodistribution of Two CDKL5 Gene Therapy Vector Leads
Dolan Sondhi, PhD
Weill Cornell Medicine
$150,000
Awardee: Dolan Sondhi, PhD
Institution: Weill Cornell Medicine
Award Amount: $150,000
Funding Period: May 1, 2021 - April 31, 2022
Advancing a mosaic CDKL5 zebrafish model for high-throughput screening approaches
Christopher McGraw, MD, PhD
Boston Children's Hospital
$150,000
Awardee: Christopher McGraw, MD, PhD
Institution: Boston Children's Hospital
Award Amount: $150,000
Funding Period: May 1, 2021 - April 31, 2022
Defining ciliary signaling and targets in CDKL5 Deficiency Disorder
Peter K. Jackson, PhD
Stanford University School of Medicine
$150,000
Awardee: Peter K. Jackson, PhD
Institution: Stanford University School of Medicine
Award Amount: $150,000
Funding Period: May 1, 2021 - April 31, 2022
Impact of Cdkl5 deficiency on cortical dynamics and network architecture
Michael J. Higley, MD, PhD
Yale University
$150,000
Awardee: Michael J. Higley, MD, PhD
Institution: Yale University
Award Amount: $150,000
Funding Period: May 1, 2021 - April 31, 2022
Systems Analysis of the CDKL5-Deficiency Disorder (CDKL5-DD) Cerebrospinal Fluid Proteome
Victor Faundez, MD, PhD
Emory University
$150,000
Awardee: Victor Faundez, MD, PhD
Institution: Emory University
Award Amount: $150,000
Funding Period: May 1, 2021 - April 31, 2022
Characterization and correction of Cdkl5 nuclear function in human CDD neurons during maturation
Simone DiGiovanni, MD, PhD
Imperial College London
$149,277
Awardee: Simone DiGiovanni, MD, PhD
Institution: Imperial College London
Award Amount: $149,277
Elucidate the neural mechanisms underlying sleep disturbances and the relation between seizures and sleep-wake cycle in CDKL5 deficiency disorder (CDD)
Liqin Cao, PhD
Tsukuba University
$139,940
Awardee: Liqin Cao, PhD
Institution: Tsukuba University
Award Amount: $139,940
Visualizing the effect of CDKL5 deficiency on ciliary core structures
Alan Brown, PhD
Harvard Medical School
$150,000
Awardee: Alan Brown, PhD
Institution: Harvard Medical School
Award Amount: $150,000
Incorporation of functional unnatural amino acids into CDKL5 to study its function in cells
Maolin Guo, PhD
University of Massachusetts, Dartmouth
$150,000
Awardee: Maolin Guo, PhD
Institution: University of Massachusetts, Dartmouth
Award Amount: $150,000
Ascertaining the cell-autonomous effects of CDKL5 mutations in every brain cell type
Steven A. McCarroll, PhD
Harvard Medical School
$140,000
Awardee: Steven A. McCarroll, PhD
Institution: Harvard Medical School
Award Amount: $140,000
Assessing peripheral sensory neuron dysfunction in animal models for CDKL5 deficiency disorder
Lauren Orefice, PhD
Massachusetts General Hospital
$150,000
Awardee: Lauren Orefice, PhD
Institution: Massachusetts General Hospital
Award Amount: $150,000