Structural/functional characterization of full-length hCDKL5 isoform 1 produced in recombinant marine bacteria and use of pharmacological chaperones to stabilize hCDKL5 missense mutants

CDKL5CDKL5 Pilot Grant Programme

Jun 1

Written By Million Dollar Bike Ride

Awardee: Maria Luisa Tutino, PhD

Institution: University of Naples

Award Amount: $148,300

CDKL52020

Million Dollar Bike Ride

CDKL5 regulation of ciliary assembly and signaling

MEK inhibition for RASopathy associated hypertrophic cardiomyopathy