Awarded Grants
Awarded Grants
Incorporation of functional unnatural amino acids into CDKL5 to study its function in cells
Maolin Guo, PhD
University of Massachusetts, Dartmouth
$150,000
Awardee: Maolin Guo, PhD
Institution: University of Massachusetts, Dartmouth
Award Amount: $150,000
Ascertaining the cell-autonomous effects of CDKL5 mutations in every brain cell type
Steven A. McCarroll, PhD
Harvard Medical School
$140,000
Awardee: Steven A. McCarroll, PhD
Institution: Harvard Medical School
Award Amount: $140,000
Assessing peripheral sensory neuron dysfunction in animal models for CDKL5 deficiency disorder
Lauren Orefice, PhD
Massachusetts General Hospital
$150,000
Awardee: Lauren Orefice, PhD
Institution: Massachusetts General Hospital
Award Amount: $150,000
CDKL5 regulation of ciliary assembly and signaling
Gregory J. Pazour, PhD
University of Massachusetts Medical School
$150,000
Awardee: Gregory J. Pazour, PhD
Institution: University of Massachusetts Medical School
Award Amount: $150,000
Structural/functional characterization of full-length hCDKL5 isoform 1 produced in recombinant marine bacteria and use of pharmacological chaperones to stabilize hCDKL5 missense mutants
Maria Luisa Tutino, PhD
University of Naples
$148,300
Awardee: Maria Luisa Tutino, PhD
Institution: University of Naples
Award Amount: $148,300
What are the functional consequences of CDKL5 dysfunction in human neuronal cells?
Nicole Van Bergen
Murdoch Children's Research Institute
$55,898
Awardee: Nicole Van Bergen
Institution: Murdoch Children's Research Institute
Award Amount: $55,898
Validation of pupil size as a biomarker for CDKL5 disorder: longitudinal assessment and relationship with disease severity
Tommaso Pizzorusso
University of Florence, Department NEUROFARBA
$51,382
Awardee: Tommaso Pizzorusso
Institution: University of Florence, Department NEUROFARBA
Award Amount: $51,382
Funding Period: February 1, 2019 - January 31, 2020
Zebrafish as model to analyze CDKL5 function
M. Leonor Cancela
University of Algarve/DCBM and Centre of Marine Sciences
$51,382
Awardee: M.Leonor Cancela
Institution: University of Algarve/DCBM and Centre of Marine Sciences
Award Amount: $51,382
Funding Period: February 1, 2019 - January 31, 2020
The neuropathology of CDKL5 disorder
Delia Talos
University of Pennsylvania SOM
$51,160
Awardee: Delia Talos
Institution: University of Pennsylvania SOM
Award Amount: $51,160
Funding Period: January 1, 2018 - December 31, 2018
Neuronal determinants of CDKL5 deficiency disorder: neuropathological, genetic and molecular analysis of postmortem brains
Maurizio Giustetto
University of Torino
$51,160
Awardee: Maurizio Giustetto
Institution: University of Torino
Award Amount: $51,160
Funding Period: January 1, 2018 - December 31, 2018
Neurophysiological correlates in CDKL5 syndrome: a supplement to the NIH Natural History Study of Rett syndrome, CDKL5 syndrome, and other Rett syndrome-related disorders
Eric Marsh and Tim Benke
University of Colorado and CHOP
53,500
Awardee: Eric Marsh & Tim Benke
Institution: University of Colorado and CHOP
Award Amount: $53,500
Funding Period: January 1, 2017 - December 31, 2017
Sensory evoked potentials as a biomarker in CDKL5
Charles Nelson
Harvard
$53,500
Awardee: Charles Nelson
Institution: Harvard
Award Amount: $53,500
Funding Period: January 1, 2017 - December 31, 2017