The ODC is offering 42 research opportunities focusing on 34 different rare diseases. This program provides a one-year grant to support research related to a rare disease represented in the 2024 Million Dollar Bike Ride. Number of awards and dollar amounts vary per disease based on fundraising totals by each disease team.

The MDBR 2024 Pilot Grants are open to the international community holding a faculty‐level appointment at an academic institution or a senior scientific position at a non-profit institution or foundation

Full Applications (by invitation only) are Due:

Monday, October 21, 2024 by 8PM EST.

To Apply:

Step 1 - Please review the 2024 MDBR Pilot Grant Program RFA Guidelines.

Step 2 - Download and complete the below forms:

Step 3 - Complete the Application Form on Submittable.

Research Areas for the 2024 MDBR Grant Program:

1. Adult Polyglucosan Body Disease (APBD)

2. Ataxia-Telangiectasia (A-T)

3. BPAN- A Neurodegeneration with Brain Iron Accumulation Disorder

4. CACNA1A-Related Disorders

5. CADASIL

6. Castleman Disease

7. CDKL5 Deficiency Disorder

8. Choroideremia (CHM)

9. Complex Lymphatic Anomalies (CLA)

10. Congenital Hyperinsulinism (CHI)

11. Congenital Muscular Dystrophy (CMD)

12. Cohen Syndrome (COH)

13. CRB1

14. CSNK2A1

15. CTNNB1

16. Dup15q

17. Dyskeratosis Congenita & Telomere Biology Disorder

18. Fibrous Dysplasia/McCune Albright Syndrome

19. Glut1 Deficiency Syndrome

20. KCNT1

21. Lesch-Nyhan Syndrome (LNS)

22. Lymphangioleiomyomatosis (LAM)

23. Mucopolysaccharidoses (MPS)

24. MPS Gene Spotlight: Mucopolysaccharidosis (MPS I)

25. Neuroendocrine cell Hyperplasia of Infancy (NEHI)

26. Pitt Hopkins Syndrome (PTHS)

27. RASopathies

28. Ring 14

29. SCN2A

30. Schinzel-Giedion Syndrome (SGS)

31. SETBP1 Haploinsufficiency Disorder

32. STXBP1 Encephalopathy

33. SynGAP1

34. TBC1D24

35. ZC4H2

Submittable is up and running. Due to the unforeseen technical difficulties we are extending the deadline until Sunday, Sept 22nd at 8pm.

The ODC is offering 42 research opportunities focusing on 34 different rare diseases. This program provides a one-year grant to support research related to a rare disease represented in the 2024 Million Dollar Bike Ride. Number of awards and dollar amounts vary per disease based on fundraising totals by each disease team.

Letter of Interest (LOI) Applications are Due Sunday, September 22nd, 2024 by 8pm ET

To Apply:

1. Please review the Request for Applications (RFA)

2. Complete the Application Form on Submittable.

The MDBR 2024 Pilot Grants are open to the international community holding a faculty‐level appointment at an academic institution or a senior scientific position at a non-profit institution or foundation.

Prior MDBR award recipients must have current and updated project reporting to be eligible for selection.

Research Areas for the 2024 MDBR Grant Program:

1. Adult Polyglucosan Body Disease (APBD)

2. Ataxia-Telangiectasia (A-T)

3. BPAN- A Neurodegeneration with Brain Iron Accumulation Disorder

4. CACNA1A-Related Disorders

5. CADASIL

6. Castleman Disease

7. CDKL5 Deficiency Disorder

8. Choroideremia (CHM)

9. Complex Lymphatic Anomalies (CLA)

10. Congenital Hyperinsulinism (CHI)

11. Congenital Muscular Dystrophy (CMD)

12. Cohen Syndrome (COH)

13. CRB1

14. CSNK2A1

15. CTNNB1

16. Dup15q

17. Dyskeratosis Congenita & Telomere Biology Disorder

18. Fibrous Dysplasia/McCune Albright Syndrome

19. Glut1 Deficiency Syndrome

20. KCNT1

21. Lesch-Nyhan Syndrome (LNS)

22. Lymphangioleiomyomatosis (LAM)

23. Mucopolysaccharidoses (MPS)

24. MPS Gene Spotlight: Mucopolysaccharidosis (MPS I)

25. Neuroendocrine cell Hyperplasia of Infancy (NEHI)

26. Pitt Hopkins Syndrome (PTHS)

27. RASopathies

28. Ring 14

29. SCN2A

30. Schinzel-Giedion Syndrome (SGS)

31. SETBP1 Haploinsufficiency Disorder

32. STXBP1 Encephalopathy

33. SynGAP1

34. TBC1D24

35. ZC4H2

The ODC is offering 39 research opportunities focusing on 31 different rare diseases. This program provides a one-year grant to support research related to a rare disease represented in the 2023 Million Dollar Bike Ride. Number of awards and dollar amounts vary per disease based on fundraising totals by each disease team.

The MDBR 2023 Pilot Grants are open to the international community holding a faculty‐level appointment at an academic institution or a senior scientific position at a non-profit institution or foundation

Full Applications (by invitation only) are Due Monday, October 16, 2023 by 8PM EST.

To Apply:

Step 1 - Please review the 2023 MDBR Pilot Grant Program RFA Guidelines.

Step 2 - Download and complete the below forms:

Step 3 - Complete the Application Form on Submittable.

Research Areas for the 2023 MDBR Grant Program:

1. Adult Polyglucosan Body Disease (APBD)

2. Ataxia-Telangiectasia (A-T)

3. BPAN- A Neurodegeneration with Brain Iron Accumulation Disorder

4. CACNA1A

5. CADASIL

6. Castleman Disease

7. CDKL5 Deficiency Disorder

8. Choroideremia (CHM)

9. Complex Lymphatic Anomalies (CLA)

10. Congenital Hyperinsulinism (CHI)

11. Congenital Muscular Dystrophy (CMD)

12. Cohen Syndrome (COH)

13. Dup15q

14. Dyskeratosis Congenita & Telomere Biology Disorder

15. Fibrous Dysplasia/McCune Albright Syndrome

16. Glut1 Deficiency Sundrome

17. KCNT1

18. Lesch-Nyhan Syndrome (LNS)

19. Lymphangioleiomyomatosis (LAM)

20. Mucopolysaccharidoses (MPS)

21. MPS Gene Spotlight: Mucopolysaccharidosis (MPS I)

22. Neuroendocrine cell Hyperplasia of Infancy (NEHI)

23. Niemann-Pick Type C (NPC)

24. Pitt Hopkins Syndrome (PTHS)

25. RASopathies

26. Ring 14

27. SCN2A

28. SETBP1 Haploinsufficiency Disorder

29. STXBP1 Encephalopathy

30. SynGAP1

31. TBC1D24

32. ZC4H2

The ODC is offering 39 research opportunities focusing on 31 different rare diseases. This program provides a one-year grant to support research related to a rare disease represented in the 2023 Million Dollar Bike Ride. Number of awards and dollar amounts vary per disease based on fundraising totals by each disease team.

Letter of Interest (LOI) Applications are Due Friday, September 15th, 2023 by 8pm ET

To Apply:

1. Please review the Request for Applications (RFA)

2. Complete the Application Form on Submittable.

The MDBR 2023 Pilot Grants are open to the international community holding a faculty‐level appointment at an academic institution or a senior scientific position at a non-profit institution or foundation.

Prior MDBR award recipients must have current and updated project reporting to be eligible for selection.

Research Areas for the 2023 MDBR Grant Program:

1. Adult Polyglucosan Body Disease (APBD)

2. Ataxia-Telangiectasia (A-T)

3. BPAN- A Neurodegeneration with Brain Iron Accumulation Disorder

4. CACNA1A

5. CADASIL

6. Castleman Disease

7. CDKL5 Deficiency Disorder

8. Choroideremia (CHM)

9. Complex Lymphatic Anomalies (CLA)

10. Congenital Hyperinsulinism (CHI)

11. Congenital Muscular Dystrophy (CMD)

12. Cohen Syndrome (COH)

13. Dup15q

14. Dyskeratosis Congenita & Telomere Biology Disorder

15. Fibrous Dysplasia/McCune Albright Syndrome

16. Glut1 Deficiency Sundrome

17. KCNT1

18. Lesch-Nyhan Syndrome (LNS)

19. Lymphangioleiomyomatosis (LAM)

20. Mucopolysaccharidoses (MPS)

21. MPS Gene Spotlight: Mucopolysaccharidosis (MPS I)

22. Neuroendocrine cell Hyperplasia of Infancy (NEHI)

23. Niemann-Pick Type C (NPC)

24. Pitt Hopkins Syndrome (PTHS)

25. RASopathies

26. Ring 14

27. SCN2A

28. SETBP1 Haploinsufficiency Disorder

29. STXBP1 Encephalopathy

30. SynGAP1

31. TBC1D24

32. ZC4H2

The ODC is offering 39 research opportunities focusing on 31 different rare diseases. This program provides a one-year grant to support research related to a rare disease represented in the 2023 Million Dollar Bike Ride. Number of awards and dollar amounts vary per disease based on fundraising totals by each disease team.

LOI Extension for select disease (see below for list of diseases)

Letter of Interest (LOI) Applications are extended for select disease & Due Friday, October 6th, 2023 by 8pm ET

To Apply:

1. Please review the Request for Applications (RFA)

2. Complete the Application Form on Submittable.

The MDBR 2023 Pilot Grants are open to the international community holding a faculty‐level appointment at an academic institution or a senior scientific position at a non-profit institution or foundation.

Prior MDBR award recipients must have current and updated project reporting to be eligible for selection.

EXTENDED LOI DUE DATE IS FOR THE BELOW DISEASE TEAMS

Research Areas for the 2023 MDBR Grant Program:

1. Adult Polyglucosan Body Disease (APBD)

2. Choroideremia (CHM)

3. Ring 14

4. Niemann-Pick Type C (NPC)

5. TBC1D24

6. Neuroendocrine cell Hyperplasia of Infancy (NEHI)

7. SETBP1 Haploinsufficiency Disorder

The ODC is offering 41 research opportunities focusing on 30 different rare diseases. This program provides a one-year grant to support research related to a rare disease represented in the 2022 Million Dollar Bike Ride. Number of awards and dollar amounts vary per disease based on fundraising totals by each disease team.

Extended deadline for specific diseases: Letter of Interest (LOI) Applications are Due Friday, October 7th, 2022 by 8pm EST

To Apply:

1. Please review the Request for Applications (RFA)

2. Complete the Application Form on Submittable.

The MDBR 2022 Pilot Grants are open to the international community holding a faculty‐level appointment at an academic institution or a senior scientific position at a non-profit institution or foundation

Research Areas for the 2022 MDBR Grant Program:

1. Adult Polyglucosan Body Disease (APBD)

2. Ataxia-Telangiectasia (A-T)

3. BPAN- A Neurodegeneration with Brain Iron Accumulation Disorder

4. CADASIL

5. Castleman Disease

6. CDKL5 Deficiency Disorder

7. Choroideremia (CHM)

8. Complex Lymphatic Anomalies (CLA)

9. Congenital Hyperinsulinism (CHI)

10. Congenital Muscular Dystrophy (CMD)

11. Cohen Syndrome (COH)

12. Dyskeratosis Congenita & Telomere Biology Disorder

13. Fibrous Dysplasia/McCune Albright Syndrome

14. Glut1 Deficiency Sundrome

15. Lesch-Nyhan Syndrome (LNS)

16. Lymphangioleiomyomatosis (LAM)

17. Mucopolysaccharidoses (MPS)

18. MPS Gene Spotlight: Mucopolysaccharidosis (MPS I)

19. Maple Syrup Urine Disease (MSUD)

20. Mitochondrial Complex 1 Deficiency Disorder - NUBPL

21. Mucolipidosis Type IV (ML4)

22. Neuroendocrine cell Hyperplasia of Infancy (NEHI)

23. Pitt Hopkins Syndrome (PTHS)

24. RASopathies

25. SCN2A

26. SETBP1 Disorder

27. STXBP1 Encephalopathy

28. SynGAP1

29. TBC1D24

30. TBCK Syndrome

31. ZC4H2

The ODC is offering 41 research opportunities focusing on 30 different rare diseases. This program provides a one-year grant to support research related to a rare disease represented in the 2022 Million Dollar Bike Ride. Number of awards and dollar amounts vary per disease based on fundraising totals by each disease team.

The MDBR 2022 Pilot Grants are open to the international community holding a faculty‐level appointment at an academic institution or a senior scientific position at a non-profit institution or foundation

Full Application (by invitation only) are Due Monday, October 17, 2022 by 8 PM EST.

To Apply:

Step 1 - Please review the 2022 MDBR Pilot Grant Program RFA Guidelines.

Step 2 - Download and complete the below forms:

Step 3 - Complete the Application Form on Submittable.

Research Areas for the 2022 MDBR Grant Program:

1. Adult Polyglucosan Body Disease (APBD)

2. Ataxia-Telangiectasia (A-T)

3. BPAN- A Neurodegeneration with Brain Iron Accumulation Disorder

4. CADASIL

5. Castleman Disease

6. CDKL5 Deficiency Disorder

7. Choroideremia (CHM)

8. Complex Lymphatic Anomalies (CLA)

9. Congenital Hyperinsulinism (CHI)

10. Congenital Muscular Dystrophy (CMD)

11. Cohen Syndrome (COH)

12. Dyskeratosis Congenita & Telomere Biology Disorder

13. Fibrous Dysplasia/McCune Albright Syndrome

14. Glut1 Deficiency Sundrome

15. Lesch-Nyhan Syndrome (LNS)

16. Lymphangioleiomyomatosis (LAM)

17. Mucopolysaccharidoses (MPS)

18. MPS Gene Spotlight: Mucopolysaccharidosis (MPS I)

19. Maple Syrup Urine Disease (MSUD)

20. Mitochondrial Complex 1 Deficiency Disorder - NUBPL

21. Mucolipidosis Type IV (ML4)

22. Neuroendocrine cell Hyperplasia of Infancy (NEHI)

23. Pitt Hopkins Syndrome (PTHS)

24. RASopathies

25. SCN2A

26. SETBP1 Disorder

27. STXBP1 Encephalopathy

28. SynGAP1

29. TBC1D24

30. TBCK Syndrome

31. ZC4H2

The ODC is offering 42 research opportunities focusing on 29 different rare diseases. This program provides a one-year grant to support research related to a rare disease represented in the 2021 Million Dollar Bike Ride. Number of awards and dollar amounts vary per disease based on fundraising totals by each disease team.

Full Applications are Due Monday, October 18, 2021 by 8pm EST, by invitation only.

To Apply:

1. Please review the Request for Applications (RFA)

2. Complete Cover Page to be uploaded with full application

3. Complete Budget Form to be uploaded with full application

4. Complete the Application Form on Submittable.
   

The MDBR 2021 Pilot Grants are open to the international community holding a faculty‐level appointment at an academic institution or a senior scientific position at a non-profit institution or foundation

Research Areas for the 2021 MDBR Grant Program:

1. Adult Polyglucosan Body Disease (APBD)

2. Ataxia-Telangiectasia (A-T)

3. BPAN- A Neurodegeneration with Brain Iron Accumulation Disorder

4. CADASIL

5. Castleman Disease

6. CDKL5 Deficiency Disorder

7. Choroideremia (CHM)

8. Complex Lymphatic Anomalies (CLA)

9. Congenital Hyperinsulinism (CHI)

10. Congenital Muscular Dystrophy (CMD)

11. Cohen Syndrome (COH)

12. Nonsense Mutations in Cystic Fibrosis

13. Dyskeratosis Congenita & Telomere Biology Disorder

14. Fibrous Dysplasia/McCune Albright Syndrome

15. Fibrodysplasia Ossificans Progressiva (FOP)

16. Glut1 Deficiency Sundrome

17. Lymphangioleiomyomatosis (LAM)

18. Mucopolysaccharidoses (MPS)

19. MPS Gene Spotlight: Mucopolysaccharidosis (MPS I)

20. Maple Syrup Urine Disease (MSUD)

21. Mitochondrial Complex 1 Deficiency Disorder - NUBPL

22. Mucolipidosis Type IV (ML4)

23. Neuroendocrine cell Hyperplasia of Infancy (NEHI)

24. Niemann Pick Type C (NPC)

25. Pitt Hopkins Syndrome (PTHS)

26. RASopathies

27. SETBP1 Disorder

28. Snyder-Robinson Syndrome (SRS)

29. STXBP1 Encephalopathy

30. TBCK Syndrome

The ODC is offering 38 research opportunities focusing on 29 different rare diseases. This program provides a one-year grant to support research related to a rare disease represented in the 2020 Million Dollar Bike Ride. Number of awards and dollar amounts vary per disease based on fundraising totals by each disease team.

Research Areas for the 2020 MDBR Grant Program:

1. Adult Polyglucosan Body Disease (APBD)

2. Ataxia-Telangiectasia (A-T)

3. BPAN- A Neurodegeneration with Brain Iron Accumulation Disorder

4. CADASIL

5. Castleman Disease

6. Choroideremia

7. Congenital Hyperinsulinism (CHI)

8. Congenital Muscular Dystrophy (CMD)

9. Charcot Maire Tooth (CMT)

10. Cohen Syndrome (COH)

11. Nonsense Mutations in Cystic Fibrosis

12. Dyskeratosis Congenita & Telomere Biology Disorder

13. Fibrous Dysplasia/McCune Albright Syndrome

14. Fibrodysplasia Ossificans Progressiva (FOP)

15. Generalized Lymphatic Anomaly (GLA; a.k.a. lymphangiomatosis) and Gorham-Stout Disease (GSD)

16. Glut1 Deficiency Sundrome

17. Inclusion Body Myositis (IBM)

18. Lymphangioleiomyomatosis (LAM)

19. Mucopolysaccharidoses (MPS)

20. MPS Gene Spotlight: Mucopolysaccharidosis (MPS I)

21. Maple Syrup Urine Disease (MSUD)

22. Mitochondrial Complex 1 Deficiency Disorder - NUBPL

23. Neuroendocrine cell Hyperplasia of Infancy (NEHI)

24. Niemann Pick Type C (NPC)

25. Pitt Hopkins Syndrome (PTHS)

26. RASopathies

27. SETBP1 Disorder

28. Snyder-Robinson Syndrome (SRS)

29. STXBP1 Encephalopathy

30. TBCK Syndrome